The church was one of the tituli, the first parish churches of Rome. It was probably built in the 4th century under Pope Silvester I (314–335), rebuilt in the 12th century by John of Crema, and again by Giovanni Battista Soria, funded by Scipione Borghese, in the early 17th century. [...] The 22 granite columns in the nave are recycled antique columns. The floor is Cosmatesque, but most of it is hidden by the pews. The confessio in the sanctuary area is from the 8th century. The high altar is from 1127, with a baldachino from (1627 or 1641) by Gian Lorenzo Bernini. The painting in the middle of the Baroque coffered ceiling is by Guercino, and depicts the Glory of Saint Chrysogonus. (Text from Wikipedia).